C-40 Truncated carbocyclic formycin derivatives
نویسندگان
چکیده
Formycin is a naturally occurring C-glycoside (C-nucleoside) that possesses antitumor, antibacterial, antifungal, and antiviral activity. In connection with our ongoing interest in the design and syntheses of C-nucleoside derived antiviral agents this report describes the preparation of carbocyclic formycin and its 7-hydroxy (oxo) analog lacking the C-40 hydroxylmethylene moiety in racemic form (4 and 6, respectively). An antiviral analysis of (!)-4 did not disclose any activity. ! 2006 Elsevier Ltd. All rights reserved.
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